Wolverine Blend (BPC-157 + TB-500)

Overview

The Wolverine Blend combines BPC-157 and TB-500, two of the most researched peptides for supporting recovery, inflammation control, and tissue repair. Together, they’re often studied for promoting faster healing, improving joint function, and helping the body recover from training or injury stress — hence the nickname “Wolverine.”

How It Works

• BPC-157 (Body Protection Compound) is a peptide fragment derived from stomach proteins. It’s being studied for its potential to promote angiogenesis, tendon and gut repair, and overall anti-inflammatory signaling.
• TB-500 (Thymosin Beta-4 fragment) supports cellular regeneration and blood vessel growth, which may accelerate recovery at the tissue level.
• When combined, they may amplify repair signaling pathways and improve healing outcomes in connective tissue, muscle, and fascia.

Potential Benefits (Research-Based)

• Support recovery of soft tissues (tendons, ligaments, muscles)
• May reduce inflammation and oxidative stress
• Enhance collagen synthesis and cellular healing
• Support joint comfort and mobility
• Promote gut-lining stability (BPC-157)
• Aid recovery after overtraining, strain, or surgery

Reported / Potential Side Effects

Research and anecdotal reports suggest few side effects, though some users have reported:
• Mild irritation at the injection site
• Temporary fatigue or light headache
• Rare localized redness or histamine response

These peptides are not approved for human use and are provided for educational purposes only.

Typical Dosing Examples (Educational)

Note: For education only. Not medical advice.

General repair / recovery: 250 – 750 mcg per day (subcutaneous)
Injury-specific / focused healing: 1 – 2 mg per day (subcutaneous), divided into 1-2 doses

Cycle length examples:
• Short-term recovery: 4 – 6 weeks
• Chronic injury / ongoing maintenance: 8 – 12 weeks (then reassess)
• Some transition to every-other-day dosing after significant improvement

Because each situation varies, always discuss with a licensed provider before use or cycling any peptide.

Pairings / Synergy

• Tesamorelin or CJC/Ipamorelin → for growth-hormone support and muscle restoration
• Retatrutide or Tirzepitide (GLP-1/GIP blends) → may complement inflammation control and metabolic repair during recovery phases
• AOD-9604 or MOTS-c → for mitochondrial and cellular energy support

Resources & Safe Sourcing

Explore trusted research sources for Wolverine (BPC-157 + TB-500) and other compounds in my Tools & Resources section at KempCoreFitness.com.

Educational Disclaimer

This information is provided for educational purposes only and is not medical advice. Always consult a qualified healthcare provider before beginning any peptide or supplement protocol.

References / Research

“The promoting effect of pentadecapeptide BPC 157 on tendon healing …” (tendon fibroblasts, migration, survival) — PubMed link:
https://pubmed.ncbi.nlm.nih.gov/21030672/ PubMed

“Pentadecapeptide BPC 157 Enhances the Growth Hormone Receptor Expression in Tendon Fibroblasts” — PMC full text:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271067/ PMC

“Gastric pentadecapeptide body protection compound BPC 157 and soft tissue healing” — review summary:
https://pubmed.ncbi.nlm.nih.gov/30915550/ PubMed

“Multifunctionality and Possible Medical Application of BPC 157” — review of mechanisms, safety, etc.:
https://pubmed.ncbi.nlm.nih.gov/40005999/ PubMed

“Thymosin β4: a multi-functional regenerative peptide” — overview of TB-4 (related to TB-500) in repair & regeneration:
https://pubmed.ncbi.nlm.nih.gov/22074294/ PubMed

“Local and Systemic Peptide Therapies for Soft Tissue Regeneration” — includes discussion of BPC-157’s effects in various injury models:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11426299/ PMC

“Emerging Use of BPC-157 in Orthopaedic Sports Medicine” — systemic review of preclinical + limited human data:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313605/ PMC

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